Translate Bio

Moderna Inc

BioNTech SE

1472 PubMed publications found for Translate Bio

Performance of Local Large Language Models for Adjudicating Heart Failure Hospitalizations.

Non-BRCA germline pathogenic variants and response to neoadjuvant systemic therapy in triple-negative breast cancer patients enrolled in a prospective clinical trial.

Evaluation of in vitro blood-brain barrier models in central nervous system new drug development: methodological challenges and translational perspectives.

AI-enhanced cardiac digital twins extend drug proarrhythmic risk assessment through experimental data uncertainty propagation and overdose exploration: A loperamide case study.

Reversible alterations of brain acetate metabolism associated with alcohol consumption.

1466 PubMed publications found for Translate Bio

Engineering skin microphysiological systems for transdermal drug screening based on strategic model selection and quantitative prediction roadmaps.

Efficacy and safety of a bodyweight-adjusted higher dose of ocrelizumab in relapsing (MUSETTE) and primary progressive (GAVOTTE) multiple sclerosis: two multicentre, randomised, double-blind, parallel-group phase 3b trials.

Safety analyses of the INAVO120 randomised phase III trial of inavolisib or placebo with palbociclib-fulvestrant in patients with PIK3CA-mutated, hormone receptor-positive, HER2-negative, endocrine-resistant advanced breast cancer.

Osimertinib plus selumetinib in patients with EGFR-mutated advanced NSCLC with BRAF alterations post-progression on first-line osimertinib: ORCHARD.

Phase 1/2 study of pegenzileukin, a pegylated recombinant non-alpha IL-2, with cemiplimab for the treatment of advanced unresectable or metastatic skin cancers.

1464 PubMed publications found for Translate Bio

Development of a translational murine model for antibody-drug conjugate-induced interstitial lung disease.

Updated trends in the global prevalence and burden of mental disorders, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

1462 PubMed publications found for Translate Bio

Chk1-Targeted Hesperidin Liposomes for Breast Cancer Therapy: An Integrated In Silico, In Vitro, and In Vivo Evaluation.

Two-Trace Two-Dimensional Correlation Analysis for the Confirmation of Therapeutic Protein Identification and Evaluation of Extent of Glycosylation: A Rapid Method for Testing Critical Quality Attributes.

1463 PubMed publications found for Translate Bio

Ginsenosides for Multi-target Intervention in Alzheimer's Disease: Current Evidence, Challenges, and Future Directions.

SW convergence: 50/100 (Neutral), 0 bullish / 0 bearish signals

1455 PubMed publications found for Translate Bio

A Phase I trial of the anti-IL23 monoclonal antibody tildrakizumab, in combination with abiraterone acetate, for the treatment of metastatic castration-resistant prostate cancer.

Impact of Anti-Inflammatory Drug Therapy on the Efficacy of First-Line Atezolizumab Treatment in Patients With Advanced Non-Small Cell Lung Cancer: An Integrated Analysis of Five Randomized Controlled Trials.

A phase 1, safety, tolerability, and pharmacokinetics study of bisnorcymserine, a highly selective inhibitor of butyrylcholinesterase.

Effectiveness and Safety of Early Rhythm Control in Patients With Atrial Fibrillation and Chronic Kidney Disease.

1449 PubMed publications found for Translate Bio

Biomaterial-based strategies for postoperative residual tumors: From margin clearance to immune control and tissue repair.

Performance-Safety-Feasibility Evidence Chains for Next-Generation Food-Preservation Packaging: Engineering and Regulatory Prioritization of Bio-Based, Nano-Enabled, and Intelligent Systems.

Engineering Brain Injury In Vitro: Human iPSC-Based Organoids in Microfluidic Systems.

1444 PubMed publications found for Translate Bio

The microRNA inhibitor CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: a randomized phase 2 trial.

Evolution of bispecific and multispecific antibodies in cancer therapy.

Fibroblast Growth Factor 21: Mechanisms, Therapeutic Potential, and Clinical Translation in Metabolic Dysfunction.

Autosomal Dominant Tubulointerstitial Kidney Disease Clinical Trial Simulator: Case Reports of Model-Informed Drug Development.

1442 PubMed publications found for Translate Bio

Ferroptosis in cancer: molecular mechanisms, biological roles, and therapeutic significance.

Bench-to-Bedside Translation of Self-Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials.

1441 PubMed publications found for Translate Bio

Bio-nano architectures as therapeutic platforms: mechanism-driven precision anti-infective therapy for periodontal regeneration.

1439 PubMed publications found for Translate Bio

1437 PubMed publications found for Translate Bio

Characteristics of interventional clinical trials registered in ClinicalTrials.gov, 2018-2023.

1433 PubMed publications found for Translate Bio

Symptom-Based Dosing for Neonatal Opioid Withdrawal: The OPTimize NOW Randomized Clinical Trial.

Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma.

1430 PubMed publications found for Translate Bio

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma.

Cascade nanozyme composite hydrogels: design strategies, preparation method and biomedical applications.

1426 PubMed publications found for Translate Bio

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR-Based β-Cell Replacement and Treg Immune Modulation Approaches.

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH-SY5Y and U-87 MG cancer cells.

1428 PubMed publications found for Translate Bio

Safety considerations for cereblon-recruiting targeted protein degraders.

Advancing precision medicine in pancreatic cancer using novel biomarkers and clinical targets.

1420 PubMed publications found for Translate Bio

An overview of recent flexible- and soft-biomaterial applications in myocardial infarction and other cardiovascular diseases.

Global burden of metabolic dysfunction-associated steatotic liver disease, 1990-2023, and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2023.

Dynamics of Spinal Fluid Immune Cell Alterations Following Cladribine Tablet Treatment in Multiple Sclerosis.

1419 PubMed publications found for Translate Bio

Plasma p-tau217 and glucose metabolism correlate in neocortical association areas in Alzheimer's disease.

The role of the molecular tumor board: learnings from the ROME trial.

The Discovery of Cenobamate: A Drug with High Efficacy in Drug-Resistant Epilepsy.

1414 PubMed publications found for Translate Bio