A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

Study Summary

A phase 1/2, open-label, safety and dosing study of autologous CART cells (desmoglein 3 chimeric autoantibody receptor T cells \[DSG3-CAART\] or CD19-specific Chimeric Antigen Receptor T cells \[CABA-201\]) in subjects with active, pemphigus vulgaris

Conditions

Pemphigus Vulgaris

Interventions / Drugs

DSG3-CAART CABA-201

View on ClinicalTrials.gov ↗

Sponsor

Study Details

Enrollment40 participants

Primary Completion—

Lead SponsorCabaletta Bio

Data Retrieved2026-04-11 04:08:39.574174+00:00

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