HomeTrialNCT06999733
🔬NCT06999733Phase 1Phase 2RECRUITING

A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

Study Summary

The Sponsor is developing KB801, a replication-defective, non-integrating herpes simplex virus type 1 (HSV-1)-derived vector engineered to deliver functional full-length human nerve growth factor (NGF) to the corneas of people with Stage 2 or 3 neurotrophic keratitis (NK) via topical application. This is a Phase 1/2, multicenter, double-masked, placebo-controlled study to evaluate the safety, tolerability, and preliminary efficacy of KB801 in these subjects.

Interventions / Drugs
View on ClinicalTrials.gov ↗
Study Details
Enrollment60 participants
Primary Completion
Lead SponsorKrystal Biotech, Inc.
Data Retrieved2026-04-11 04:19:09.549341+00:00
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