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NCT07400588Phase 2Active, not recruiting

Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

Study Summary

The purpose of this study is to assess the safety and tolerability of aleniglipron at doses up to 240 mg once daily (QD) in participants with T2DM who are living with obesity (body mass index \[BMI\] ≥ 30 kg/m2) or overweight (BMI ≥ 27 kg/m2).

Interventions / Drugs
View on ClinicalTrials.gov ↗
Study Details
Enrollment58 participants
Primary Completion2026-09
Lead SponsorGasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Data Retrieved2026-10-14
What This Trial Means for Biotech Investors
Trial Phase Context

Phase 2 trials begin testing efficacy in a larger patient group (100–300). This is often where biotech binary events occur — positive Phase 2 data can significantly advance a company's pipeline narrative, while failures can be terminal for a program.

Status & Expected Data

Enrollment is complete. The trial is in its follow-up or data collection phase — a readout may occur on or near the primary completion date.

Primary completion: 2026-09
Enrolled: 58 participants
Sponsor Catalyst Profile

Structure Therapeutics (GPCR) is the sponsoring company for this trial. BiotechSign currently grades this company C (50/100) based on composite catalyst signals across its full pipeline. This trial is one data point in that overall catalyst picture.

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