Screen & Filter Biotech Signals

Each row is a biotech company with active signals from FDA filings, SEC disclosures, clinical trial databases, and insider trading records. Use the filters below to surface the companies worth researching before the market moves.

How to Use This Screener
What is the Grade?

A–F letter grade based on the quality and timing of upcoming catalysts — PDUFA dates, AdCom votes, Phase 3 readouts. A = multiple near-term high-impact events. F = nothing on the calendar.

What is the Score?

0–100 composite measuring signal density across all data sources. A score of 80+ means multiple independent signals are firing simultaneously — insider buys, clinical activity, and an approaching FDA date, for example.

What is a Catalyst?

A scheduled event with a known date that can move a biotech stock significantly — FDA approval decisions (PDUFA), advisory committee votes (AdCom), Phase 2/3 trial data readouts, and earnings.

What are Signals?

Tags showing which data sources fired. PDUFA = approval date. Insider Buy = executive bought shares. Convergence = StonkWhisper momentum aligned with fundamentals. Dilution = SEC filing suggests offering risk.

What is Dilution Risk?

DilutionWatch score (0–100) measuring SEC-filing evidence of upcoming share dilution. CRITICAL = active S-3/ATM shelf, offering likely this quarter. LOW = healthy balance sheet, no shelf detected.

What is Cash Runway?

Estimated months of cash remaining at the current burn rate from DilutionWatch. A company cannot survive to its PDUFA date without cash. Under 6 months = likely to raise capital soon.

Top companies from the BiotechSign screener, including ticker, company name, catalyst grade, score, sector, and upcoming FDA catalyst context.

BGNE - BeiGene LtdGrade A, score 88, OncologyKPTI - Karyopharm TherapeuticsGrade A, score 87, OncologyGRI - GRI Bio, Inc.Grade A, score 83, Biotech / PharmaMRUS - Merus NVGrade A, score 82, Bispecific AntibodiesDNLI - Denali TherapeuticsGrade B, score 79, NeuroscienceAMAG - AMAG PharmaceuticalsGrade B, score 78, HematologyITCI - Intra-Cellular TherapiesGrade B, score 78, NeuroscienceHRMY - Harmony BiosciencesGrade B, score 77, NeuroscienceEXEL - Exelixis IncGrade B, score 76, OncologyITOS - iTeos TherapeuticsGrade B, score 76, OncologyMGNX - MacroGenics IncGrade B, score 75, OncologyRNAC - Cartesian Therapeutics, Inc.Grade B, score 74, Biotech / PharmaSGEN - Seagen IncGrade B, score 74, Oncology ADCJAZZ - Jazz Pharmaceuticals plcGrade B, score 73, Biotech / PharmaALPN - Alpine Immune SciencesGrade B, score 70, ImmunologyIMVT - Immunovant IncGrade B, score 68, AutoimmuneONCY - Oncolytics Biotech, Inc.Grade B, score 65, OncologyVNDA - Vanda PharmaceuticalsGrade B, score 65, NeuroscienceARDX - Ardelyx IncGrade C, score 65, NephrologyNKTR - Nektar TherapeuticsGrade C, score 65, ImmunologyPHVS - Pharvaris NVGrade C, score 64, Rare DiseaseAGIO - Agios PharmaceuticalsGrade C, score 64, Rare DiseaseDAWN - Day One BiopharmaceuticalsGrade C, score 64, Pediatric OncologyAKBA - Akebia TherapeuticsGrade C, score 64, NephrologyVRDN - Viridian Therapeutics, Inc.Grade C, score 64, Biotech / PharmaIVVD - Invivyd IncGrade C, score 64, Infectious DiseaseIBRX - ImmunityBio, Inc.Grade C, score 64, Biotech / PharmaBNTX - BioNTech SEGrade C, score 64, mRNA TherapeuticsPTCT - PTC TherapeuticsGrade C, score 64, Rare DiseaseAKRO - Akero TherapeuticsGrade C, score 64, Metabolic DiseaseMRNA - Moderna IncGrade C, score 63, mRNA TherapeuticsVKTX - Viking TherapeuticsGrade C, score 63, Metabolic DiseaseTYRA - Tyra BiosciencesGrade C, score 63, Precision MedicineBIIB - Biogen IncGrade C, score 63, NeuroscienceGENB - Generate Biomedicines, Inc.Grade C, score 63, Biotech / PharmaCATX - Perspective TherapeuticsGrade C, score 63, OncologyAIM - AIM ImmunoTech Inc.Grade C, score 62, ImmunologyEYPT - EyePoint, Inc.Grade C, score 62, OphthalmologyACLX - Arcellx IncGrade C, score 62, Cell TherapyFDMT - 4D Molecular Therapeutics, Inc.Grade C, score 62, Biotech / PharmaVRTX - Vertex PharmaceuticalsGrade C, score 62, Gene TherapyIDYA - IDEAYA BiosciencesGrade C, score 62, Precision OncologyNUVL - Nuvalent IncGrade C, score 62, OncologyCDTX - Cidara TherapeuticsGrade C, score 61, OncologySGP - SpyGlass Pharma, Inc.Grade C, score 61, Biotech / PharmaPBYI - Puma Biotechnology IncGrade C, score 61, Biotech / PharmaVIR - Vir Biotechnology, Inc.Grade C, score 61, Biotech / PharmaBCAB - BioAtla IncGrade C, score 61, OncologyARQT - Arcus BiosciencesGrade C, score 61, Immuno-OncologyTGTX - TG TherapeuticsGrade C, score 61, Oncology
Total Companies
50
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Showing 50 of 50 companies
TickerCompanySectorScoreGradeDW RiskCashSignalsNext Catalyst
BGNEBeiGene LtdOncology
87.86
A
KPTIKaryopharm TherapeuticsOncology
87.01
A
GRIGRI Bio, Inc.Biotech / Pharma
83.36
A
MRUSMerus NVBispecific Antibodies
82.49
A
DNLIDenali TherapeuticsNeuroscience
78.93
B
AMAGAMAG PharmaceuticalsHematology
78.28
B
ITCIIntra-Cellular TherapiesNeuroscience
78.28
B
HRMYHarmony BiosciencesNeuroscience
77.42
B
EXELExelixis IncOncology
76.22
B
ITOSiTeos TherapeuticsOncology
76.18
B
MGNXMacroGenics IncOncology
74.79
B
RNACCartesian Therapeutics, Inc.Biotech / Pharma
74.27
B
SGENSeagen IncOncology ADC
74.07
B
JAZZJazz Pharmaceuticals plcBiotech / Pharma
73.01
B
ALPNAlpine Immune SciencesImmunology
69.87
B
IMVTImmunovant IncAutoimmune
68.45
B
ONCYOncolytics Biotech, Inc.Oncology
65.19
B
VNDAVanda PharmaceuticalsNeuroscience
65.1
B
ARDXArdelyx IncNephrology
64.98
C
NKTRNektar TherapeuticsImmunology
64.89
C
PHVSPharvaris NVRare Disease
64.47
C
AGIOAgios PharmaceuticalsRare Disease
64.37
C
DAWNDay One BiopharmaceuticalsPediatric Oncology
64.31
C
AKBAAkebia TherapeuticsNephrology
64.29
C
VRDNViridian Therapeutics, Inc.Biotech / Pharma
64.28
C
IVVDInvivyd IncInfectious Disease
64.27
C
IBRXImmunityBio, Inc.Biotech / Pharma
64.19
C
BNTXBioNTech SEmRNA Therapeutics
63.9
C
PTCTPTC TherapeuticsRare Disease
63.9
C
AKROAkero TherapeuticsMetabolic Disease
63.64
C
MRNAModerna IncmRNA Therapeutics
63.16
C
VKTXViking TherapeuticsMetabolic Disease
63.16
C
TYRATyra BiosciencesPrecision Medicine
63.07
C
BIIBBiogen IncNeuroscience
62.93
C
GENBGenerate Biomedicines, Inc.Biotech / Pharma
62.57
C
CATXPerspective TherapeuticsOncology
62.55
C
AIMAIM ImmunoTech Inc.Immunology
62.45
C
EYPTEyePoint, Inc.Ophthalmology
62.26
C
ACLXArcellx IncCell Therapy
62.05
C
FDMT4D Molecular Therapeutics, Inc.Biotech / Pharma
61.95
C
VRTXVertex PharmaceuticalsGene Therapy
61.68
C
IDYAIDEAYA BiosciencesPrecision Oncology
61.61
C
NUVLNuvalent IncOncology
61.54
C
CDTXCidara TherapeuticsOncology
61.45
C
SGPSpyGlass Pharma, Inc.Biotech / Pharma
61.36
C
PBYIPuma Biotechnology IncBiotech / Pharma
61.25
C
VIRVir Biotechnology, Inc.Biotech / Pharma
61.2
C
BCABBioAtla IncOncology
60.88
C
ARQTArcus BiosciencesImmuno-Oncology
60.76
C
TGTXTG TherapeuticsOncology
60.71
C

Not financial advice. Data by Guerilla Finance Inc. for informational purposes only. Always conduct your own due diligence.