Puma Biotechnology Inc (PBYI)
BiotechSign Signal Grade
Composite of clinical trial activity, dilution exposure, publications, short interest, and insider transactions — all from verified public filings.
Pipeline Overview
- Therapeutic Focus
- Biotech / Pharmasrc
Clinical Trial Activity
(ClinicalTrials.gov aggregate)
ClinicalTrials.gov aggregate as of 2026-10-07. ClinicalTrials.gov
Dilution Risk
MEDIUM DILUTION RISKDilution score: 26/100 (MEDIUM), cash runway not available
Derived from verified regulatory filings. Measures dilution exposure from warrants, convertibles, and offering history. DilutionWatch SEC-derived score
Short Interest
Short interest: 11.05% of float, squeeze risk: MODERATE
FINRA short sale data. FINRA short interest
Recent News & SEC Filings
- PBYI's Alisertib Combo Phase II Study in Small Cell Lung Cancer Begins
- Puma Biotechnology Initiates ALISCA®-Lung2, a Phase II Trial of Alisertib in Combination with Paclitaxel for the Treatment of Patients with Advanced Small Cell Lung Cancer
- Puma Biotechnology to Present at H.C. Wainwright’s 28th Annual Global Investment Conference
- Puma Biotechnology (PBYI) Q2 2026 Earnings Call Transcript
- Is Puma Biotechnology (PBYI) a Great Value Stock Right Now?
- Puma Biotechnology Inc (PBYI) (Q2 2026) Earnings Call Highlights: Debt-Free Status and Raised ...
- Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)
- PBYI Q2 Earnings & Sales Beat Estimates, 2026 Guidance Raised
Headlines from public sources. BiotechSign does not endorse or verify linked content.
Recent Publications
- Diffusion histogram analysis predicts progression-free survival in contrast enhancing recurrent IDH mutant gliomas treated with bevacizumab. — J Neurooncol 2026 Sep 9 PMID 42717134
- pH- and ROS-Responsive Polyurethane/Polylysine Nanomicelles Delivering Leonurine Attenuate Inflammation and Cartilage Damage in Experimental Rheumatoid Arthritis. — Int J Nanomedicine 2026 PMID 42699353
- Single-fraction or multi-fraction stereotactic ablative body radiotherapy followed by atezolizumab in advanced triple-negative breast cancer: a randomized phase II trial. — Nat Commun 2026 Jul 27 PMID 42649154
- A Phase Ib/II Study of Atezolizumab in Combination with Thiopurine Therapy in Patients with Metastatic Solid Tumors and Intermediate Tumor Mutational Burden. — Cancer Res Commun 2026 Sep 1 PMID 42647116
- Manual, digital, and AI tumour-infiltrating lymphocyte scoring: a secondary analysis of the APHINITY randomised trial. — Lancet Oncol 2026 Sep PMID 42636838
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