Live Sentinel Network Active

Every Biotech Catalyst.
Before The Market Moves.

FDA PDUFA dates, insider filings, and clinical trial data across 981 biotech companies — scored, ranked, and updated daily.

What does BiotechSigns track?

BiotechSigns tracks FDA PDUFA dates, insider buying, clinical trial activity, dilution risk, short interest, congressional trades, and convergence signals across 981 biotech companies. The platform updates daily and currently shows 2,375 active catalyst signals.

981
Companies Tracked
2,375
Active Signals
3
Live Sentinels
24/7
Monitoring
125+
PDUFA Dates

PDUFA Date Calendar

BiotechSigns monitors FDA decision deadlines and surfaces upcoming PDUFA dates with company, drug, indication, and timing context.

Clinical Trial Readouts

Clinical trial signals summarize active studies, trial phase, recruitment activity, and company-level catalyst density from ClinicalTrials.gov data.

Insider Buying Signals

Insider buying signals track SEC Form 4 activity and highlight clusters where executives or directors recently purchased shares.

Freshness and Provenance

This page was refreshed on 2026-05-18. Data comes from FDA, SEC EDGAR, ClinicalTrials.gov, DilutionWatch, StonkWhisper, and internal signal scoring jobs.

Real-Time Intelligence

Live Signal Feed

Filtered by signal type — updated daily by our sentinel network

No PDUFA signals loaded
AI-Scored Rankings

Top Scored Companies

#TickerCompanyScoreGradeSector
Research Workflows

How Biotech Investors Use BTS

Not financial advice — these are common research workflows that investors apply when using catalyst intelligence platforms.

🗓
The PDUFA Calendar Play

Investor wants to identify biotech companies with FDA approval decisions in the next 30 days.

Research Steps
1.Open the Screener → toggle Catalyst Only
2.Sort by Next Catalyst (ascending)
3.Filter Grade ≥ B to remove thin-pipeline companies
4.Click any ticker to see full signal history, DW dilution risk, and StonkWhisper momentum
Why BTS: PDUFA dates are public but scattered. BTS consolidates them in one sortable calendar with risk context.
👤
The Insider Cluster Buy Screen

Multiple insiders at the same company bought shares in the last 30 days — often a leading indicator.

Research Steps
1.Open Screener → Signal filter: Insider Buy
2.Sort by Score descending to surface the most active companies
3.Look for tickers where Insider Buy appears alongside Clinical or PDUFA tags
4.Check the company page for the specific Form 4 filing details
Why BTS: A single insider buy is noise. Three insiders buying in 30 days is a pattern. BTS surfaces the cluster.
⚠️
The Dilution Risk Screen

Trader wants to identify biotech stocks at high risk of a dilutive offering before it happens.

Research Steps
1.Open Screener → Signal filter: Dilution
2.Sort by Score descending
3.Companies flagged with both Dilution + Short Int. signals face double pressure
4.Cross-reference cash runway — companies with <6 months cash are near-certain to offer
Why BTS: Dilution destroys biotech returns. BTS integrates DilutionWatch data to flag S-3 filings and ATM risk.
🔬
The Phase 3 Readout Watch

Research analyst tracking upcoming Phase 2→3 transitions and primary completion dates.

Research Steps
1.Open Screener → Signal filter: Clinical
2.Filter Grade A or B — companies with both clinical activity and other signals
3.Sort by Score to find the densest signal overlap
4.Dig into the company page for trial details from ClinicalTrials.gov
Why BTS: Phase 3 data readouts move stocks 40–100%+. BTS maps trial phase counts and upcoming dates in one view.
📈
The Momentum + Catalyst Combo

Swing trader looking for biotech names where technical momentum and fundamental catalysts align.

Research Steps
1.Open Screener → Signal filter: Convergence
2.Convergence means StonkWhisper momentum signal fired alongside fundamental data
3.Combine with Grade A/B filter for the strongest combined signal
4.These companies have both price momentum and an upcoming event — the highest-conviction setups
Why BTS: StonkWhisper integration is unique to BTS. Momentum + catalyst convergence reduces false positive rate.
🏛
The Congress Trade Tracker

Investor tracking when sitting members of Congress buy biotech stocks ahead of FDA decisions.

Research Steps
1.Open Screener → Signal filter: Congress
2.Sort by Score — companies where the Congress signal co-occurs with other signals
3.Cross-check the company page for the specific STOCK Act disclosure details
4.Combine with PDUFA filter to find Congress trades near upcoming FDA decisions
Why BTS: Congress members are required to disclose trades under STOCK Act. BTS surfaces biotech-sector trades automatically.
How It Works

Your Information Edge, Automated

🛰
Sentinels Scan

Three always-on sentinels scrape SEC EDGAR, ClinicalTrials.gov, and FDA databases daily across every tracked biotech company.

Signals Fire

When a catalyst is detected — PDUFA deadline, insider Form 4, trial phase update — a scored signal is generated with context and timeline.

📊
You Stay Ahead

Browse the screener, set watchlist alerts, and dig into company deep-dives with full signal history and DW/SW data overlays.

Pricing

Simple, Transparent Pricing

Start free. Unlock everything when you need the edge.

FREE
$0
Forever free
  • 7-day PDUFA calendar
  • 5 ticker lookups/day
  • Signal feed (basic)
  • DW / SW data overlay
  • Full signal history
  • API access
MOST POPULAR
PRO
$19/mo
Cancel anytime
  • Unlimited ticker lookups
  • Full 90-day PDUFA calendar
  • All signal types + history
  • DilutionWatch data overlay
  • StonkWhisper sentiment
  • News feed per ticker
  • API access
  • Priority support
Not financial advice. Data by Guerilla Finance Inc. for informational purposes only. Nothing here constitutes investment advice. Always conduct your own due diligence.